Basic Cardiovascular Science 2020 Scientific Sessions is supported by an independent medical education grant from: Merck and Novartis Pharmaceuticals North America.
Monday
2:00 pm3:00 pm (CDT) Jul 27, 2020

Moderated Poster Session 1A | Sarcomeric Function & Contractility


View this Moderated Poster Session by clicking HERE. (Posters are embargoed until the listed time.) 

Poster Discussant: Danish Sayed, PhD, Newark, New Jersey

MP 100

Scalable Functional Classification of Heart Failure-Associated Genetic Variants in Cardiac Troponin T

Anthony M. Pettinato, Feria A. Ladha, Univ of Connecticut, Farmington, CT; David Mellert, Nicholas Legere, Rachel Cohn, The Jackson Lab, Farmington, CT; Robert Romano, Univ of Connecticut, Farmington, CT; Ketan Thakar, Yu-Sheng Chen, The Jackson Lab, Farmington, CT; John Travis Hinson, Univ of Connecticut, Farmington, CT

MP 101

Functional Maintenance of the Sarcomere Requires Bag3-Dependent Autophagy

Thomas G. Martin, Loyola Univ Chicago, Oak Park, IL; Arthur M. Feldman, Temple Univ Sch of Med, Philadelphia, PA; Monte S. Willis, Indiana Univ Sch of Med, Indianapolis, IN; Jonathan A. Kirk, Loyola Univ Chicago, Maywood, IL

MP 102

Skeletal Muscle Alpha Actin Acetylation Enhances Myosin Binding and Increases Calcium Sensitivity In Vitro

Samantha S. Romanick, Allison Matsumura, Travis Stewart, Kianna Boc, Univ of Nevada Reno, Reno, NV; Jonathan Baker, Bradley S. Ferguson, Univ of Nevada Reno, Reno, NV

MP 103

Methylglyoxal Modifications on Myofilament Proteins Caused by Diabetes Block Heart Failure Drug Targets Through Changing Tropomyosin Position

Maria Papadaki, Theerachat Kampaengsri, Loyola Univ Chicago, Maywood, IL; Samantha Barrick, Washington Univ, St. Louis, MO; Stuart Campbell, Yale Univ, New Haven, CT; Michael Greenberg, Washington Univ, St. Louis, MO; Jonathan A. Kirk, Loyola Univ Chicago, Maywood, IL

MP 104

Phosphodiesterase 1 Modulates Sarcolemmal CAMP to Increase the L-Type Calcium Channel Activity and Induce Cardiomyocyte Contraction

Grace K. Muller, Johns Hopkins Sch of Med, Baltimore, MD; Joy Song, Johns Hopkins Univ, Baltimore, MD; Vivek Jani, Johns Hopkins Univ–MSTP, Baltimore, MD; Yuejin Wu, Johns Hopkins Univ–MSTP, Baltimore, MD; Manuela Zaccolo, Univ of Oxford, Oxford; David Alan Kass, Johns Hopkins Med Inst, Baltimore, MD  

MP 105

Python Post-Prandial Cardiac Adaptation Is Supported by Enhanced Metabolism, Reduced Sarcomere Passive Tension and Epigenetic Remodeling  

Claudia Crocini, Univ of Colorado Boulder, Boulder, CO; KC Woulfe, Univ of Colorado, Aurora, CO; Cierra J. Walker, Christopher D. Ozeroff, Univ of Colorado Boulder, Boulder, CO; Leslie A. Leinwand, Univ of Colorado, Boulder, CO